Shengjian Li Selected Research

Adrenergic Antagonists (Antiadrenergic Agents)

1/2008	(Phenylpiperazinyl)cyclohexylureas: discovery of alpha1a/1d-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).
11/2007	Aminocyclohexylsulfonamides: discovery of metabolically stable alpha(1a/1d)-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).
7/2007	(Phenylpiperidinyl)cyclohexylsulfonamides: development of alpha1a/1d-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).
6/2007	(Arylpiperazinyl)cyclohexylsufonamides: discovery of alpha(1a/1d)-selective adrenergic receptor antagonists for the treatment of Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms (BPH/LUTS).

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Shengjian Li Research Topics

Disease

5	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 01/2008 - 03/2007
5	Lower Urinary Tract Symptoms 01/2008 - 03/2007
4	Macular Degeneration (Age-Related Maculopathy) 01/2016 - 11/2014
3	Neoplasms (Cancer) 10/2015 - 08/2007
2	Colorectal Neoplasms (Colorectal Cancer) 01/2016 - 10/2015
2	Geographic Atrophy 11/2014 - 11/2014
2	Obesity 05/2006 - 04/2005
1	Fibrosarcoma 01/2016
1	Autoimmune Diseases (Autoimmune Disease) 01/2016
1	Corneal Neovascularization 01/2016
1	Melanoma (Melanoma, Malignant) 10/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2015
1	Iron Overload 06/2015
1	Blindness (Hysterical Blindness) 11/2014
1	Weight Gain 04/2005

Drug/Important Bio-Agent (IBA)

4	Adrenergic Antagonists (Antiadrenergic Agents)IBA 01/2008 - 06/2007
4	alpha-1 Adrenergic Receptors (alpha 1 Adrenergic Receptor)IBA 01/2008 - 03/2007
3	InflammasomesIBA 06/2015 - 11/2014
2	melanin-concentrating hormone receptorIBA 05/2006 - 04/2005
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2016
1	BGB-283IBA 10/2015
1	dabrafenibIBA 10/2015
1	VemurafenibIBA 10/2015
1	Antineoplastic Agents (Antineoplastics)IBA 10/2015
1	raf KinasesIBA 10/2015
1	IronIBA 06/2015
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 11/2014
1	Retroelements (Retrotransposon)IBA 11/2014
1	RNA (Ribonucleic Acid)IBA 11/2014
1	Retinaldehyde (Retinal)IBA 11/2014
1	Interleukin-18 (Interleukin 18)IBA 11/2014
1	Caspase 8 (Caspase-8)IBA 11/2014
1	EnzymesIBA 11/2014
1	pyrazoleIBA 08/2007
1	benzocycloheptapyridineIBA 08/2007
1	melanin-concentrating hormone (melanin concentrating hormone)IBA 05/2006

Therapy/Procedure

1	Therapeutics 01/2016